Lemon balm is derived from controlled sources of cultivation for pharmaceutical processing. It is a perennial plant grown in Germany, but also in Eastern Europe. Lemon balm is a heat-loving and relatively drought-resistant plant that grows in sandy to loamy, but also humus-rich soils. It is either grown from seedlings, cuttings or by sowing seeds in spring. Seedlings are nurtured inside a greenhouse from March to April and then planted outside from April to August. Cuttings are grown through vegetative propagation of the parent plants in a greenhouse or outdoors between April and August. The parent plant can be cut 3 to 4 times a year and planted in propagators. Once the head cuttings have taken root, they can be planted outside. Seeds are sown in May when the ground is warmer.

Weed control takes place mechanically or using specific pesticides that are permitted in lemon balm production and is strictly regulated by the Legislation on Plant Protection Products. The plant or seed must receive an adequate supply of water throughout the year, particularly after each cutting so that the plant can successfully regenerate.

Harvesting takes place using a modified combine harvester before the formatation of flower buds. A later harvest increases the proportion of stems. The leaves are quickly processed after harvesting to prevent the plant from deteriorating. The leaves are first trimmed and cleaned. The trimmed leaves are then dried using various drying methods to prevent any nutrient loss.